A pharmaceutical distributor ships 500,000 vaccine doses per year, each costing $45. With 25% arriving degraded due to cold chain failures, the annual waste is:
\[\text{Annual Waste} = 500,000 \times 0.25 \times \$45 = \$5,625,000\]
Time-Temperature Indicator (TTI) smart packaging costs $0.85 per dose (tag + cloud logging), reducing degradation to 3%:
\[\text{New Waste} = 500,000 \times 0.03 \times \$45 = \$675,000\] \[\text{Packaging Cost} = 500,000 \times \$0.85 = \$425,000\]
Net annual savings: \(\$5,625,000 - \$675,000 - \$425,000 = \$4,525,000\).
The payback period is: \[\text{Payback Months} = \frac{\$425,000}{\$4,525,000 / 12} \approx 1.1 \text{ months}\]
After payback, the monthly benefit is approximately \(\$377,000\).